node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hisA | hisF | gene:10500434 | gene:10499065 | Phosphorybosilformimino-5-amino-phosphorybosil- 4-imidazolecarboxamideisomerase; ORF_ID:slr0652. | Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). | 0.997 |
hisA | trpA | gene:10500434 | gene:10497731 | Phosphorybosilformimino-5-amino-phosphorybosil- 4-imidazolecarboxamideisomerase; ORF_ID:slr0652. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.411 |
hisA | trpB | gene:10500434 | gene:10500341 | Phosphorybosilformimino-5-amino-phosphorybosil- 4-imidazolecarboxamideisomerase; ORF_ID:slr0652. | Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.402 |
hisA | trpC | gene:10500434 | gene:10500369 | Phosphorybosilformimino-5-amino-phosphorybosil- 4-imidazolecarboxamideisomerase; ORF_ID:slr0652. | Indole-3-glycerol phosphate synthase; ORF_ID:slr0546; Belongs to the TrpC family. | 0.937 |
hisA | trpF | gene:10500434 | gene:10499418 | Phosphorybosilformimino-5-amino-phosphorybosil- 4-imidazolecarboxamideisomerase; ORF_ID:slr0652. | 5'-phosphoribosyl anthranilate isomerase; ORF_ID:sll0356; Belongs to the TrpF family. | 0.936 |
hisF | hisA | gene:10499065 | gene:10500434 | Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). | Phosphorybosilformimino-5-amino-phosphorybosil- 4-imidazolecarboxamideisomerase; ORF_ID:slr0652. | 0.997 |
hisF | trpA | gene:10499065 | gene:10497731 | Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.461 |
hisF | trpB | gene:10499065 | gene:10500341 | Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). | Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.461 |
hisF | trpC | gene:10499065 | gene:10500369 | Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). | Indole-3-glycerol phosphate synthase; ORF_ID:slr0546; Belongs to the TrpC family. | 0.603 |
hisF | trpE | gene:10499065 | gene:10497544 | Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). | Anthranilate synthetase alpha-subunit; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high conc [...] | 0.560 |
hisF | trpE-2 | gene:10499065 | gene:10499089 | Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). | Anthranilate synthase component I; ORF_ID:slr1979. | 0.433 |
hisF | trpF | gene:10499065 | gene:10499418 | Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). | 5'-phosphoribosyl anthranilate isomerase; ORF_ID:sll0356; Belongs to the TrpF family. | 0.879 |
sll1634 | trpA | gene:10498358 | gene:10497731 | ORF_ID:sll1634; unknown protein. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.952 |
sll1634 | trpB | gene:10498358 | gene:10500341 | ORF_ID:sll1634; unknown protein. | Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.929 |
sll1634 | trpC | gene:10498358 | gene:10500369 | ORF_ID:sll1634; unknown protein. | Indole-3-glycerol phosphate synthase; ORF_ID:slr0546; Belongs to the TrpC family. | 0.956 |
sll1634 | trpD | gene:10498358 | gene:10498529 | ORF_ID:sll1634; unknown protein. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.770 |
sll1634 | trpE | gene:10498358 | gene:10497544 | ORF_ID:sll1634; unknown protein. | Anthranilate synthetase alpha-subunit; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high conc [...] | 0.978 |
sll1634 | trpE-2 | gene:10498358 | gene:10499089 | ORF_ID:sll1634; unknown protein. | Anthranilate synthase component I; ORF_ID:slr1979. | 0.976 |
sll1634 | trpF | gene:10498358 | gene:10499418 | ORF_ID:sll1634; unknown protein. | 5'-phosphoribosyl anthranilate isomerase; ORF_ID:sll0356; Belongs to the TrpF family. | 0.948 |
sll1634 | trpG | gene:10498358 | gene:10499779 | ORF_ID:sll1634; unknown protein. | Anthranilate synthase component II; ORF_ID:slr0055. | 0.920 |