STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nirAFerredoxin--nitrite reductase; ORF_ID:slr0898; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (502 aa)    
Predicted Functional Partners:
narB
Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
 
  
 0.994
glnA
Glutamate--ammonia ligase; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
     
 0.981
glnN
Glutamate--ammonia ligase; ORF_ID:slr0288; Belongs to the glutamine synthetase family.
     
 0.969
cysH
3'-phosphoadenosine-5'-phosphosulfate sulfotransferase; Reduction of activated sulfate into sulfite; Belongs to the PAPS reductase family. CysH subfamily.
  
 0.958
gdhA
Glutamate dehydrogenase (NADP+); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
     
 0.931
hemD
uroporphyrin-III synthase; ORF_ID:sll0166; Belongs to the precorrin methyltransferase family.
 
  
 0.907
cysG
uroporphyrin-III C-methyltransferase; Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-2; their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin.
 
  
 0.907
merR-2
Nitrilase; ORF_ID:sll0784.
     
 0.903
gltB-2
Ferredoxin-dependent glutamate synthase; ORF_ID:sll1499; Belongs to the glutamate synthase family.
   
 
 0.870
ntcA
Global nitrogen regulator; Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control.
      
 0.841
Your Current Organism:
Synechocystis sp. PCC6803
NCBI taxonomy Id: 1148
Other names: Aphanocapsa sp. (strain N-1), Aphanocapsa sp. N-1, S. sp. PCC 6803, Synechocystis sp. (ATCC 27184), Synechocystis sp. (PCC 6803), Synechocystis sp. (strain PCC 6803), Synechocystis sp. ATCC 27184, Synechocystis sp. PCC 6803, Synechocystis sp. PCC 6803 A, Synechocystis sp. PCC 6803 B
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