node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ackA | acs | gene:10498051 | gene:10500002 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.993 |
ackA | slr0091 | gene:10498051 | gene:10500068 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Aldehyde dehydrogenase; ORF_ID:slr0091; Belongs to the aldehyde dehydrogenase family. | 0.926 |
ackA | slr1192 | gene:10498051 | gene:10500612 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Zinc-containing alcohol dehydrogenase family; ORF_ID:slr1192. | 0.427 |
acs | ackA | gene:10500002 | gene:10498051 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.993 |
acs | mmsB | gene:10500002 | gene:10499732 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 3-hydroxyisobutyrate dehydrogenase; ORF_ID:slr0229; Belongs to the HIBADH-related family. | 0.831 |
acs | slr0091 | gene:10500002 | gene:10500068 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde dehydrogenase; ORF_ID:slr0091; Belongs to the aldehyde dehydrogenase family. | 0.948 |
cyp-2 | slr0091 | gene:10500000 | gene:10500068 | Cytochrome P450; ORF_ID:slr0574. | Aldehyde dehydrogenase; ORF_ID:slr0091; Belongs to the aldehyde dehydrogenase family. | 0.910 |
cyp-2 | slr1192 | gene:10500000 | gene:10500612 | Cytochrome P450; ORF_ID:slr0574. | Zinc-containing alcohol dehydrogenase family; ORF_ID:slr1192. | 0.739 |
gad | merR-2 | gene:10497925 | gene:10500221 | Glutamate decarboxylase; ORF_ID:sll1641; Belongs to the group II decarboxylase family. | Nitrilase; ORF_ID:sll0784. | 0.805 |
gad | panC/kcy | gene:10497925 | gene:10499038 | Glutamate decarboxylase; ORF_ID:sll1641; Belongs to the group II decarboxylase family. | Pantothenate synthetase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.942 |
gad | slr0091 | gene:10497925 | gene:10500068 | Glutamate decarboxylase; ORF_ID:sll1641; Belongs to the group II decarboxylase family. | Aldehyde dehydrogenase; ORF_ID:slr0091; Belongs to the aldehyde dehydrogenase family. | 0.919 |
merR-2 | gad | gene:10500221 | gene:10497925 | Nitrilase; ORF_ID:sll0784. | Glutamate decarboxylase; ORF_ID:sll1641; Belongs to the group II decarboxylase family. | 0.805 |
merR-2 | slr0091 | gene:10500221 | gene:10500068 | Nitrilase; ORF_ID:sll0784. | Aldehyde dehydrogenase; ORF_ID:slr0091; Belongs to the aldehyde dehydrogenase family. | 0.910 |
mmsB | acs | gene:10499732 | gene:10500002 | 3-hydroxyisobutyrate dehydrogenase; ORF_ID:slr0229; Belongs to the HIBADH-related family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.831 |
mmsB | slr0091 | gene:10499732 | gene:10500068 | 3-hydroxyisobutyrate dehydrogenase; ORF_ID:slr0229; Belongs to the HIBADH-related family. | Aldehyde dehydrogenase; ORF_ID:slr0091; Belongs to the aldehyde dehydrogenase family. | 0.936 |
panC/kcy | gad | gene:10499038 | gene:10497925 | Pantothenate synthetase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Glutamate decarboxylase; ORF_ID:sll1641; Belongs to the group II decarboxylase family. | 0.942 |
panC/kcy | slr0091 | gene:10499038 | gene:10500068 | Pantothenate synthetase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Aldehyde dehydrogenase; ORF_ID:slr0091; Belongs to the aldehyde dehydrogenase family. | 0.932 |
sll0990 | slr0091 | gene:10498026 | gene:10500068 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Aldehyde dehydrogenase; ORF_ID:slr0091; Belongs to the aldehyde dehydrogenase family. | 0.991 |
sll0990 | slr0942 | gene:10498026 | gene:10499278 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Aldehyde reductase; Aldo/keto reductase with broad substrate spectrum. Catalyzes the NADPH-dependent reduction of aldehyde- and ketone-groups of different classes of carbonyl compounds to the corresponding alcohols. Highest enzymatic efficiency is observed with 4-oxonon-2-enal (4-ONE) and 4-hydroxynon-2-enal (4-HNE), that are lipid peroxidation products, and 9,10-phenanthrenequinone (9,10-PQ), a photoproduct of phenanthrene that is one of the most prevalent polycyclic aromatic hydrocarbons in the environment. Is also active on sugar-derived reactive carbonyls such as methylglyoxal (MG) [...] | 0.994 |
sll0990 | slr1192 | gene:10498026 | gene:10500612 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Zinc-containing alcohol dehydrogenase family; ORF_ID:slr1192. | 0.982 |