node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cobW | smtB | gene:10500081 | gene:10500210 | CobW protein; ORF_ID:slr0502. | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | 0.572 |
lexA | ntcA | gene:10498637 | gene:10498881 | SOS function regulatory protein; A probable transcription regulator, probably involved in carbon metabolism. Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription. A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5'-CTA-N(9)-CTA-3' in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA. Binds to the crhR gene, represses its transcription. Belongs to the p [...] | Global nitrogen regulator; Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control. | 0.714 |
lexA | smtB | gene:10498637 | gene:10500210 | SOS function regulatory protein; A probable transcription regulator, probably involved in carbon metabolism. Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription. A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5'-CTA-N(9)-CTA-3' in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA. Binds to the crhR gene, represses its transcription. Belongs to the p [...] | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | 0.740 |
merR | smtB | gene:10500207 | gene:10500210 | Mercuric resistance operon regulatory protein; ORF_ID:sll0794; gene:merR or cobH. | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | 0.716 |
ntcA | lexA | gene:10498881 | gene:10498637 | Global nitrogen regulator; Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control. | SOS function regulatory protein; A probable transcription regulator, probably involved in carbon metabolism. Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription. A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5'-CTA-N(9)-CTA-3' in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA. Binds to the crhR gene, represses its transcription. Belongs to the p [...] | 0.714 |
ntcA | smtB | gene:10498881 | gene:10500210 | Global nitrogen regulator; Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control. | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | 0.550 |
sll0729 | smtB | gene:10500525 | gene:10500210 | Modification methylase; ORF_ID:sll0729. | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | 0.546 |
sll0793 | slr0798 | gene:10500209 | gene:10500211 | ORF_ID:sll0793; hypothetical protein. | Unknown protein; ORF_ID:slr0798; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | 0.519 |
sll0793 | smtB | gene:10500209 | gene:10500210 | ORF_ID:sll0793; hypothetical protein. | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | 0.926 |
sll0990 | smtB | gene:10498026 | gene:10500210 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | 0.549 |
slr0240 | smtB | gene:10497557 | gene:10500210 | ORF_ID:slr0240; unknown protein. | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | 0.714 |
slr0798 | sll0793 | gene:10500211 | gene:10500209 | Unknown protein; ORF_ID:slr0798; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | ORF_ID:sll0793; hypothetical protein. | 0.519 |
slr0798 | smtB | gene:10500211 | gene:10500210 | Unknown protein; ORF_ID:slr0798; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | 0.961 |
slr1788 | smtB | gene:10497659 | gene:10500210 | ORF_ID:slr1788; unknown protein. | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | 0.543 |
smtB | cobW | gene:10500210 | gene:10500081 | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | CobW protein; ORF_ID:slr0502. | 0.572 |
smtB | lexA | gene:10500210 | gene:10498637 | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | SOS function regulatory protein; A probable transcription regulator, probably involved in carbon metabolism. Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription. A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5'-CTA-N(9)-CTA-3' in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA. Binds to the crhR gene, represses its transcription. Belongs to the p [...] | 0.740 |
smtB | merR | gene:10500210 | gene:10500207 | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | Mercuric resistance operon regulatory protein; ORF_ID:sll0794; gene:merR or cobH. | 0.716 |
smtB | ntcA | gene:10500210 | gene:10498881 | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | Global nitrogen regulator; Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control. | 0.550 |
smtB | sll0729 | gene:10500210 | gene:10500525 | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | Modification methylase; ORF_ID:sll0729. | 0.546 |
smtB | sll0793 | gene:10500210 | gene:10500209 | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | ORF_ID:sll0793; hypothetical protein. | 0.926 |