node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
comEc | recA | gene:10497987 | gene:10500629 | ComE; ORF_ID:sll1929; comE ORF3. | RecA gene product; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.900 |
comEc | recQ | gene:10497987 | gene:10498325 | ComE; ORF_ID:sll1929; comE ORF3. | ATP-dependent DNA helicase; DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.698 |
comEc | sms | gene:10497987 | gene:10499369 | ComE; ORF_ID:sll1929; comE ORF3. | Sms protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. Belongs to the RecA family. RadA subfamily. | 0.533 |
comEc | uvrD | gene:10497987 | gene:10498370 | ComE; ORF_ID:sll1929; comE ORF3. | DNA helicase II; ORF_ID:sll1143; gene:uvrD or mutU. | 0.425 |
dnaB | polA | gene:10500020 | gene:10500252 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | 0.822 |
dnaB | recA | gene:10500020 | gene:10500629 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | RecA gene product; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.947 |
dnaB | recQ | gene:10500020 | gene:10498325 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | ATP-dependent DNA helicase; DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.852 |
dnaB | sms | gene:10500020 | gene:10499369 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | Sms protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. Belongs to the RecA family. RadA subfamily. | 0.610 |
dnaB | topA | gene:10500020 | gene:10498733 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.565 |
dnaB | uvrD | gene:10500020 | gene:10498370 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | DNA helicase II; ORF_ID:sll1143; gene:uvrD or mutU. | 0.746 |
lexA | polA | gene:10498637 | gene:10500252 | SOS function regulatory protein; A probable transcription regulator, probably involved in carbon metabolism. Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription. A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5'-CTA-N(9)-CTA-3' in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA. Binds to the crhR gene, represses its transcription. Belongs to the p [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | 0.512 |
lexA | recA | gene:10498637 | gene:10500629 | SOS function regulatory protein; A probable transcription regulator, probably involved in carbon metabolism. Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription. A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5'-CTA-N(9)-CTA-3' in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA. Binds to the crhR gene, represses its transcription. Belongs to the p [...] | RecA gene product; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.998 |
lexA | recN | gene:10498637 | gene:10499347 | SOS function regulatory protein; A probable transcription regulator, probably involved in carbon metabolism. Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription. A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5'-CTA-N(9)-CTA-3' in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA. Binds to the crhR gene, represses its transcription. Belongs to the p [...] | DNA repair protein; May be involved in recombinational repair of damaged DNA. | 0.905 |
lexA | recQ | gene:10498637 | gene:10498325 | SOS function regulatory protein; A probable transcription regulator, probably involved in carbon metabolism. Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription. A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5'-CTA-N(9)-CTA-3' in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA. Binds to the crhR gene, represses its transcription. Belongs to the p [...] | ATP-dependent DNA helicase; DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.515 |
lexA | sms | gene:10498637 | gene:10499369 | SOS function regulatory protein; A probable transcription regulator, probably involved in carbon metabolism. Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription. A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5'-CTA-N(9)-CTA-3' in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA. Binds to the crhR gene, represses its transcription. Belongs to the p [...] | Sms protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. Belongs to the RecA family. RadA subfamily. | 0.669 |
lexA | umuC | gene:10498637 | gene:10500200 | SOS function regulatory protein; A probable transcription regulator, probably involved in carbon metabolism. Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription. A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5'-CTA-N(9)-CTA-3' in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA. Binds to the crhR gene, represses its transcription. Belongs to the p [...] | UmuC protein; ORF_ID:slr0790. | 0.911 |
lexA | uvrD | gene:10498637 | gene:10498370 | SOS function regulatory protein; A probable transcription regulator, probably involved in carbon metabolism. Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription. A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5'-CTA-N(9)-CTA-3' in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA. Binds to the crhR gene, represses its transcription. Belongs to the p [...] | DNA helicase II; ORF_ID:sll1143; gene:uvrD or mutU. | 0.403 |
polA | dnaB | gene:10500252 | gene:10500020 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. | 0.822 |
polA | lexA | gene:10500252 | gene:10498637 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | SOS function regulatory protein; A probable transcription regulator, probably involved in carbon metabolism. Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription. A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5'-CTA-N(9)-CTA-3' in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA. Binds to the crhR gene, represses its transcription. Belongs to the p [...] | 0.512 |
polA | recA | gene:10500252 | gene:10500629 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | RecA gene product; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.992 |