node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCG07694.1 | CCG08583.1 | RSPPHO_01068 | RSPPHO_01957 | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.700 |
CCG07694.1 | fmt | RSPPHO_01068 | RSPPHO_01319 | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.877 |
CCG07694.1 | guaB | RSPPHO_01068 | RSPPHO_01069 | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.929 |
CCG07694.1 | rplC | RSPPHO_01068 | RSPPHO_01222 | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.694 |
CCG07694.1 | rplJ | RSPPHO_01068 | RSPPHO_00015 | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.782 |
CCG07694.1 | rplV | RSPPHO_01068 | RSPPHO_01227 | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. | 0.691 |
CCG07694.1 | rplX | RSPPHO_01068 | RSPPHO_01233 | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.723 |
CCG07694.1 | rpmD | RSPPHO_01068 | RSPPHO_01240 | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal protein L30. | 0.746 |
CCG07694.1 | rrmJ | RSPPHO_01068 | RSPPHO_00796 | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.838 |
CCG07694.1 | trmB | RSPPHO_01068 | RSPPHO_00188 | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.701 |
CCG08583.1 | CCG07694.1 | RSPPHO_01957 | RSPPHO_01068 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.700 |
CCG08583.1 | guaB | RSPPHO_01957 | RSPPHO_01069 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.565 |
CCG08583.1 | trmB | RSPPHO_01957 | RSPPHO_00188 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.546 |
fmt | CCG07694.1 | RSPPHO_01319 | RSPPHO_01068 | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.877 |
fmt | guaB | RSPPHO_01319 | RSPPHO_01069 | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.549 |
guaB | CCG07694.1 | RSPPHO_01069 | RSPPHO_01068 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | tRNA/rRNA cytosine-C5-methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.929 |
guaB | CCG08583.1 | RSPPHO_01069 | RSPPHO_01957 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.565 |
guaB | fmt | RSPPHO_01069 | RSPPHO_01319 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.549 |
guaB | rplC | RSPPHO_01069 | RSPPHO_01222 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.659 |
guaB | rplJ | RSPPHO_01069 | RSPPHO_00015 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.692 |