STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EL26_00800Hypothetical protein; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (486 aa)    
Predicted Functional Partners:
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
 
 0.997
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 0.996
EL26_12930
Heme peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.948
EL26_22175
Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 
 0.722
EL26_07605
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
  
 0.664
EL26_00815
Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.633
EL26_01295
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.621
EL26_06230
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.615
EL26_17585
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.575
EL26_08455
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.556
Your Current Organism:
Tumebacillus flagellatus
NCBI taxonomy Id: 1157490
Other names: CGMCC 1.12170, DSM 25748, T. flagellatus, Tumebacillus flagellatus Wang et al. 2013, Tumebacillus sp. NFB, strain GST4
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