STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UWK_01915Guanosine polyphosphate synthetase/pyrophosphohydrolase; PFAM: HD domain; TGS domain; Region found in RelA / SpoT proteins; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family. (701 aa)    
Predicted Functional Partners:
UWK_00638
Exopolyphosphatase; PFAM: Ppx/GppA phosphatase family; TIGRFAM: exopolyphosphatase.
 
 
 0.928
UWK_02087
(p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
  
 
0.926
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.919
UWK_01402
Hypothetical protein; PFAM: Region found in RelA / SpoT proteins.
     
 0.908
UWK_03176
Hypothetical protein; PFAM: Region found in RelA / SpoT proteins.
     
 0.908
UWK_00304
PFAM: Pyruvate kinase, barrel domain; Response regulator receiver domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase.
   
 
 0.907
UWK_00709
PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.907
rpsF
SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA.
  
   0.903
UWK_00318
PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
  0.900
UWK_01588
Inorganic pyrophosphatase/exopolyphosphatase; PFAM: DHH family; DHHA2 domain.
     
  0.900
Your Current Organism:
Desulfocapsa sulfexigens
NCBI taxonomy Id: 1167006
Other names: D. sulfexigens DSM 10523, Desulfocapsa sulfexigens DSM 10523, Desulfocapsa sulfexigens SB164P1, Desulfocapsa sulfexigens str. DSM 10523, Desulfocapsa sulfexigens strain DSM 10523
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.