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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
FUM6Bifunctional cytochrome P450/NADPH--P450 reductase; Bifunctional cytochrome P450/NADPH--P450 reductase; part of the gene cluster that mediates the biosynthesis of fumonisins B1 (FB1), B2 (FB2), B3 (FB3), and B4 (FB4), which are carcinogenic mycotoxins. On the basis of the chemical structures of fumonisins and precursor feeding studies, fumonisin biosynthesis is predicted to include at least five groups of biochemical reactions: synthesis of a linear polyketide with a single terminal carbonyl function and methyl groups at C-10 and C-14; condensation of the polyketide with alanine; reduc [...] (1115 aa)    
Predicted Functional Partners:
FVEG_03512
Indoleamine 2,3-dioxygenase
     
 0.901
FVEG_06565
Indoleamine 2,3-dioxygenase
     
  0.900
FVEG_09278
Hypothetical protein similar to indoleamine 2,3-dioxygenase subfamily
     
  0.900
FVEG_07269
Bifunctional P-450:NADPH-P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family
 
 
0.824
FVEG_12598
Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family
 
 
0.822
FVEG_07298
Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria
  
 
 0.763
FVEG_12090
Nitrate reductase (NADH); Hypothetical protein similar to nitrate reductase
  
 
 0.763
FVEG_01702
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family
    
 0.680
FVEG_00585
Hypothetical protein similar to aldehyde dehydrogenase 2
    
 0.670
FVEG_04346
Uncharacterized protein; Belongs to the aldehyde dehydrogenase family
    
 0.670
Your Current Organism:
Fusarium verticillioides
NCBI taxonomy Id: 117187
Other names: F. verticillioides, Fusarium moniliforme, Fusarium verticillioides, Gibberella moniliformis
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