STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ11794.1CRISPR-associated helicase, Cas3 family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3, subtype CYANO; COGs: COG1203 helicase; InterPro IPR011545:IPR014001:IPR017575; KEGG: mar:MAE_30640 DEAD/DEAH box helicase-like protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; SMART: DEAD-like helicase, N-terminal; SPTR: Similar to tr|Q3M5H2|Q3M5H2_ANAVT DEAD/DEAH box helicase-like; TIGRFAM: CRISPR-associated helicase, Cyano-type. (669 aa)    
Predicted Functional Partners:
AFZ11798.1
CRISPR-associated protein, Cas6 family; PFAM: Uncharacterized conserved protein (DUF2276); TIGRFAM: CRISPR-associated endoribonuclease Cas6; COGs: COG5551 conserved hypothetical protein; InterPro IPR019267:IPR010156; KEGG: ava:Ava_4174 CRISPR-associated Cas5e family protein; PFAM: Protein of unknown function DUF2276; SPTR: CRISPR-associated protein Cas6; TIGRFAM: CRISPR-associated protein, Cas6.
 
   
 0.943
AFZ11796.1
TIGRFAM: CRISPR type I-D/CYANO-associated protein Csc2; InterPro IPR017574; KEGG: cyp:PCC8801_0508 CRISPR-associated protein Csc2; SPTR: CRISPR-associated protein Csc2; TIGRFAM: CRISPR-associated protein Csc2.
 
     0.942
AFZ11797.1
TIGRFAM: CRISPR type I-D/CYANO-associated protein Csc1; InterPro IPR017576; KEGG: ava:Ava_4172 hypothetical protein; SPTR: CRISPR-associated protein Csc1; TIGRFAM: CRISPR-associated protein Csc1.
 
     0.942
AFZ11799.1
CRISPR-associated exonuclease, Cas4 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
  
 0.912
AFZ11795.1
TIGRFAM: CRISPR type I-D/CYANO-associated protein Csc3/Cas10d; KEGG: syp:SYNPCC7002_D0024 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.779
cas2-2
CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.687
AFZ13663.1
KEGG: npu:Npun_R2472 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.656
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.567
AFZ13670.1
KEGG: naz:Aazo_2421 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.539
cas2
CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.495
Your Current Organism:
Crinalium epipsammum
NCBI taxonomy Id: 1173022
Other names: C. epipsammum PCC 9333, Crinalium epipsammum PCC 9333, Crinalium sp. PCC 9333
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