STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ18927.1Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme (437 aa)    
Predicted Functional Partners:
AFZ20206.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain
 0.997
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
 
 0.996
AFZ21320.1
Dihydrolipoyl dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
 0.991
AFZ19603.1
PFAM: Citrate synthase; Belongs to the citrate synthase family
  
 0.965
AFZ18831.1
Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
    
 0.962
AFZ17221.1
PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron- containing alcohol dehydrogenase family
   
 
 0.948
AFZ19670.1
Succinyl-CoA synthetase, alpha subunit; PFAM: CoA binding domain
  
 0.945
AFZ17770.1
Acetyl-CoA carboxylase, biotin carboxylase subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain
  
  
 0.923
AFZ17914.1
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
   
 
 0.918
AFZ17219.1
Formate acetyltransferase 1; PFAM: Glycine radical; Pyruvate formate lyase
   
 
 0.916
Your Current Organism:
Microcoleus sp. PCC7113
NCBI taxonomy Id: 1173027
Other names: M. sp. PCC 7113, Microcoleus sp. PCC 7113, Microcoleus sp. PCC7113, Oscillatoria sp. Mc
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