STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ18927.1Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme. (437 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
AFZ20206.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.999
AFZ21320.1
Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
 0.999
AFZ19603.1
2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 0.989
AFZ19671.1
succinyl-CoA synthetase, beta subunit; PFAM: ATP-grasp domain.
  
 0.985
AFZ21266.1
NADPH-glutathione reductase; Maintains high levels of reduced glutathione.
 0.985
AFZ20336.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
 0.983
AFZ20755.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
 0.981
AFZ19670.1
succinyl-CoA synthetase, alpha subunit; PFAM: CoA binding domain.
 
 0.979
AFZ18831.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
  
 
 0.963
Your Current Organism:
Microcoleus sp. PCC7113
NCBI taxonomy Id: 1173027
Other names: Allocoleopsis franciscanus PCC 7113, M. sp. PCC 7113, Microcoleus sp. PCC 7113, Oscillatoria sp. Mc
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.