STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruAPhosphotransferase system, fructose-specific IIC component. (702 aa)    
Predicted Functional Partners:
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 
 0.999
mtlF
Mannitol-specific phosphotransferase enzyme IIA component.
 
 
 0.999
fruK
Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.999
ptsH
Phosphocarrier protein HPr.
 
 
 0.998
CDJ98854.1
Transcriptional antiterminator.
 
 
 0.992
CDK00293.1
Transcriptional regulator of sugar metabolism.
 
  
 0.992
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.976
xylA
Xylose isomerase; Belongs to the xylose isomerase family.
     
 0.962
mtlD
Mannitol-1-phosphate dehydrogenase,NAD(P)-binding; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme.
 
 
 0.956
CDJ99200.1
Putative sugar kinase; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.946
Your Current Organism:
Microbacterium sp. C448
NCBI taxonomy Id: 1177594
Other names: M. sp. C448
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.