STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCBB_0643Putative ABC transporter ATP-binding protein MJ0796; sp|Q58206|Y796_METJA;evalue=3e-055; PctID=49.78; score=214. (226 aa)    
Predicted Functional Partners:
macB-5
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. Rule:MF_01720}; Multi-pass membrane protein exporter (TC 3.A.1.122) family. Rule:MF_01720}; sp|Q6MPX9|MACB_BDEBA;evalue=2e-010; PctID=44.44; score=67.0; {ECO:0000255|HAMAP-Rule:MF_01720}.
 
 0.992
MCBB_0644
Putative protein; tr|F6D4B9|F6D4B9_METPW;evalue=2e-147; PctID=72.30; score=528; {ECO:0000313|EMBL:AEG18118,1}.
 
 0.982
MCBB_0832
Putative protein; tr|K2R3J9|K2R3J9_METFO;evalue=9e-133; PctID=70.34; score=479; {ECO:0000313|EMBL:EKF85782,1}.
 
 0.966
macB-2
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. Rule:MF_01720}; Multi-pass membrane protein exporter (TC 3.A.1.122) family. Rule:MF_01720}; sp|Q3SQZ1|MACB_NITWN;evalue=2e-010; PctID=31.21; score=67.4; {ECO:0000255|HAMAP-Rule:MF_01720}.
 
 0.963
yvrN
Putative ABC transporter permease YvrN; sp|P46324|YVRN_BACSU;evalue=3e-011; PctID=32.34; score=69.7.
 
 0.943
macB-3
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. Rule:MF_01720}; Multi-pass membrane protein exporter (TC 3.A.1.122) family. Rule:MF_01720}; sp|Q6MPX9|MACB_BDEBA;evalue=3e-016; PctID=42.99; score=86.7; {ECO:0000255|HAMAP-Rule:MF_01720}.
 
 0.927
MCBB_2177
Putative protein; tr|F6D4Y4|F6D4Y4_METPW;evalue=2e-063; PctID=53.65; score=248; {ECO:0000313|EMBL:AEG19263,1}.
 
 
 0.911
rpl2
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
   
 0.536
trxB
Thioredoxin reductase; sp|P66010|TRXB_STAAM,sp|P66011|TRXB_STAAW, sp|P99101|TRXB_STAAN,sp|Q5HHQ4|TRXB_STAAC, sp|Q6GB66|TRXB_STAAS;evalue=2e-055; PctID=42.05; score=216.
 
  
 0.474
valS
Valine-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
  
 0.452
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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