STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (222 aa)    
Predicted Functional Partners:
MCBB_1015
Putative sugar kinase AF_0356; sp|O29891|Y356_ARCFU;evalue=9e-028; PctID=48.23; score=124; Belongs to the carbohydrate kinase PfkB family.
   
 0.951
MCBB_0481
Putative sugar kinase MTH_1544; sp|O27587|Y1544_METTH;evalue=9e-009; PctID=34.91; score=61.2.
    
 0.920
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.919
aroA
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
    
 0.917
fbp
Putative protein MJ0299; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.912
MCBB_1878
Lactaldehyde dehydrogenase; Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate. lactate + NADH; sp|Q6LX65|LADH_METMP;evalue=2e-117; PctID=46.48; score=423.
  
 
 0.886
mtaC
Methanol-corrinoid protein; Harbors a corrinoid prosthetic group and acts as a methyl group carrier in methanogenesis in the methanol pathway. The methyl group of methanol is first transferred to the corrinoid prosthetic group of MtaC in the cob(I)amide oxidation state. This reaction is mediated by MtaB. The methyl group from MtaC is then transferred to coenzyme M by MtaA. ProRule:PRU00666}; sp|Q46EH4|MTAC_METBF;evalue=2e-046; PctID=39.92; score=186.
   
 
 0.877
MCBB_1382
Putative protein VNG_1688C; sp|Q06847|Y1688_HALSA;evalue=3e-014; PctID=35.90; score=79.3.
 
      0.875
MCBB_0186
Phosphoglucomutase/phosphomannomutase{03|}; Catalyzes the interconversion of glucose 1-phosphate and glucose 6-phosphate, and the interconversion of mannose 1-phosphate and mannose 6-phosphate. Also displays low activity with deoxyribose 1-phosphate and glucosamine 1-phosphate. 6-phosphate. phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Note=Can also use Ni(2+), Mn(2+) and Zn(2+), to a lesser extent; Kinetic parameters: KM=3.0 mM for glucose 1-phosphate; KM=3.2 mM for mannose 1-phosphate; KM=3.5 mM for 2-deoxyribose 1-phosphate; Vmax=690 umol/min/mg enzyme with glucose 1-ph [...]
  
 
 0.862
glmM-2
Putative phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. glucosamine 6-phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Note=Binds 1 Mg(2+) ion per subunit; Rule:MF_01554}. Sequence=AAM06397.1; Type=Erroneous initiation; Evidence=; sp|Q8TLL2|GLMM_METAC;evalue=8e-050; PctID=30.16; score=198; {ECO:0000255|HAMAP-Rule:MF_01554}.
  
 
 0.862
Your Current Organism:
Methanobacterium congolense
NCBI taxonomy Id: 118062
Other names: DSM 7095, M. congolense, Methanobacterium congolense Cuzin et al. 2001, OCM 786, strain C
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