STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa)    
Predicted Functional Partners:
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.931
AFY78346.1
acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme.
   
 
 0.931
AFY76368.1
Protein with phosphotransacetylase BioD-like N-terminal domain; PFAM: DRTGG domain.
  
  
 0.921
AFY77169.1
PFAM: Acylphosphatase.
     
 0.918
AFY79156.1
PFAM: Isocitrate lyase family.
   
  
 0.808
AFY79387.1
Phosphoketolase; PFAM: XFP N-terminal domain; D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; XFP C-terminal domain.
  
 0.791
AFY79157.1
PFAM: Malate synthase; Belongs to the malate synthase family.
   
  
 0.762
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily.
     
 0.725
AFY77344.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
  
  
 0.699
AFY77979.1
PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
  
  
 0.619
Your Current Organism:
Pleurocapsa sp. PCC7327
NCBI taxonomy Id: 118163
Other names: P. sp. PCC 7327, Pleurocapsa minor OH-69-pm, Pleurocapsa sp. ATCC 29393, Pleurocapsa sp. PCC 7327
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