STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WEN_00100COG0305 Replicative DNA helicase. (478 aa)    
Predicted Functional Partners:
WEN_01045
COG0358 DNA primase (bacterial type).
  
 
 0.995
WEN_00090
COG0629 Single-stranded DNA-binding protein.
  
 
 0.889
dnaX
DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 
 0.879
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
  
    0.782
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.704
rpsF
COG0360 Ribosomal protein S6.
       0.700
WEN_00685
DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).
  
  
 0.685
WEN_02850
DNA helicase, UvrD type; COG0210 Superfamily I DNA and RNA helicases.
  
 
 0.685
tuf
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
   0.633
WEN_02595
Elongation factor Tu; COG0050 GTPases - translation elongation factors.
   
   0.633
Your Current Organism:
Mycoplasma wenyonii
NCBI taxonomy Id: 1197325
Other names: M. wenyonii str. Massachusetts, Mycoplasma wenyonii str. Massachusetts, Mycoplasma wenyonii strain Massachusetts
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