STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0W1P5_PEDHCL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (331 aa)    
Predicted Functional Partners:
E0VRB0_PEDHC
Aspartate aminotransferase.
   
 0.966
E0VIU2_PEDHC
Aspartate aminotransferase.
   
 0.962
E0VAL8_PEDHC
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.961
E0VYZ4_PEDHC
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.961
E0VKN6_PEDHC
Malic enzyme; Belongs to the malic enzymes family.
  
 0.951
E0W3I0_PEDHC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.949
E0VA75_PEDHC
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.925
E0VYR3_PEDHC
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 
 0.924
E0W1L0_PEDHC
2-oxoisovalerate dehydrogenase, beta subunit, putative.
   
 0.922
E0V9E2_PEDHC
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.917
Your Current Organism:
Pediculus humanus
NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse
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