STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speEAgmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily. (307 aa)    
Predicted Functional Partners:
speA
Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine.
 
 
 0.983
speE-2
Hypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
 0.930
putA
Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
  
 0.623
argD
Acetylornithine aminotransferase; Identified by similarity to GP:1916298; match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.574
rpsI
30S ribosomal protein S9; Identified by similarity to EGAD:12856; match to protein family HMM PF00380; Belongs to the universal ribosomal protein uS9 family.
  
    0.534
lpdA2
Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
   
 
 0.489
NMB0470
C4-dicarboxylate transporter; Identified by similarity to EGAD:107946; match to protein family HMM PF00939; match to protein family HMM TIGR00785.
  
    0.484
efp
Elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
  
 0.461
NMB0614
Putative oxidoreductase; Identified by similarity to EGAD:29135.
 
  
 0.459
trkA
Trk system potassium uptake protein TrkA; Identified by similarity to EGAD:16153; match to protein family HMM PF02080; match to protein family HMM PF02254.
      
 0.456
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.