node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NMB2047 | apt | NMB2047 | NMB1662 | Putative hypoxanthine-guanine phosphoribosyltransferase; Identified by similarity to EGAD:77860; match to protein family HMM PF00156. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.964 |
NMB2047 | gmk | NMB2047 | NMB1661 | Putative hypoxanthine-guanine phosphoribosyltransferase; Identified by similarity to EGAD:77860; match to protein family HMM PF00156. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.938 |
NMB2047 | guaA | NMB2047 | NMB1920 | Putative hypoxanthine-guanine phosphoribosyltransferase; Identified by similarity to EGAD:77860; match to protein family HMM PF00156. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.977 |
NMB2047 | surE | NMB2047 | NMB1484 | Putative hypoxanthine-guanine phosphoribosyltransferase; Identified by similarity to EGAD:77860; match to protein family HMM PF00156. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
apt | NMB2047 | NMB1662 | NMB2047 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative hypoxanthine-guanine phosphoribosyltransferase; Identified by similarity to EGAD:77860; match to protein family HMM PF00156. | 0.964 |
apt | gmk | NMB1662 | NMB1661 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.979 |
apt | guaA | NMB1662 | NMB1920 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.998 |
apt | rpoZ | NMB1662 | NMB1660 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.491 |
apt | surE | NMB1662 | NMB1484 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.909 |
gmk | NMB2047 | NMB1661 | NMB2047 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative hypoxanthine-guanine phosphoribosyltransferase; Identified by similarity to EGAD:77860; match to protein family HMM PF00156. | 0.938 |
gmk | apt | NMB1661 | NMB1662 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.979 |
gmk | guaA | NMB1661 | NMB1920 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.971 |
gmk | ndk | NMB1661 | NMB1307 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.958 |
gmk | nrdA | NMB1661 | NMB1291 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.911 |
gmk | nrdB | NMB1661 | NMB1288 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase, beta subunit; Identified by similarity to EGAD:13866; match to protein family HMM PF00268. | 0.905 |
gmk | pykA | NMB1661 | NMB0089 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase II; Identified by similarity to EGAD:21471; match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.913 |
gmk | rpoZ | NMB1661 | NMB1660 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.982 |
gmk | spoT | NMB1661 | NMB1659 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanosine-3`,5`-bis(diphosphate) 3`-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.955 |
gmk | surE | NMB1661 | NMB1484 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.912 |
guaA | NMB2047 | NMB1920 | NMB2047 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Putative hypoxanthine-guanine phosphoribosyltransferase; Identified by similarity to EGAD:77860; match to protein family HMM PF00156. | 0.977 |