STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C494_08212COG4809 Archaeal ADP-dependent phosphofructokinase/glucokinase. (457 aa)    
Predicted Functional Partners:
pgi
COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
  
 0.947
fbp
COG0158 Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family.
     
 0.923
aroA-2
Fructose-bisphosphate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
    
 0.917
C494_19287
COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes.
    
 0.913
C494_03335
ROK family protein; COG1940 Transcriptional regulator/sugar kinase.
     
 0.911
GlmM
COG1109 Phosphomannomutase.
    
 0.908
C494_16488
Hydroxypyruvate reductase; COG2379 Putative glycerate kinase.
     
 0.825
C494_06765
COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
     
 0.822
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
     
 0.801
gdh
Molecular chaperone GroES; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.
     
  0.800
Your Current Organism:
Natronorubrum bangense
NCBI taxonomy Id: 1227500
Other names: N. bangense JCM 10635, Natronorubrum bangense JCM 10635
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