node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACO03811.1 | ACO04568.1 | PERMA_2004 | PERMA_0265 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family. | Aldolase. | 0.423 |
ACO03811.1 | fbp | PERMA_2004 | PERMA_0268 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family. | Fructose-1,6-bisphosphatase; Identified by match to protein family HMM PF00316. | 0.948 |
ACO03811.1 | pfkA | PERMA_2004 | PERMA_1298 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.927 |
ACO03811.1 | pgi | PERMA_2004 | PERMA_1557 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family. | 0.949 |
ACO03811.1 | tkt | PERMA_2004 | PERMA_1704 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family. | Transketolase; Identified by match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232; Belongs to the transketolase family. | 0.483 |
ACO04356.1 | ACO04568.1 | PERMA_0266 | PERMA_0265 | Conserved hypothetical protein. | Aldolase. | 0.773 |
ACO04356.1 | fbp | PERMA_0266 | PERMA_0268 | Conserved hypothetical protein. | Fructose-1,6-bisphosphatase; Identified by match to protein family HMM PF00316. | 0.759 |
ACO04356.1 | purA | PERMA_0266 | PERMA_0260 | Conserved hypothetical protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.648 |
ACO04568.1 | ACO03811.1 | PERMA_0265 | PERMA_2004 | Aldolase. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.423 |
ACO04568.1 | ACO04356.1 | PERMA_0265 | PERMA_0266 | Aldolase. | Conserved hypothetical protein. | 0.773 |
ACO04568.1 | fbp | PERMA_0265 | PERMA_0268 | Aldolase. | Fructose-1,6-bisphosphatase; Identified by match to protein family HMM PF00316. | 0.916 |
ACO04568.1 | pfkA | PERMA_0265 | PERMA_1298 | Aldolase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.552 |
ACO04568.1 | pgi | PERMA_0265 | PERMA_1557 | Aldolase. | Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family. | 0.877 |
ACO04568.1 | purA | PERMA_0265 | PERMA_0260 | Aldolase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.744 |
ACO04568.1 | tal | PERMA_0265 | PERMA_0911 | Aldolase. | Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.629 |
ACO04568.1 | tkt | PERMA_0265 | PERMA_1704 | Aldolase. | Transketolase; Identified by match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232; Belongs to the transketolase family. | 0.668 |
aroA-2 | fbp | PERMA_1749 | PERMA_0268 | Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | Fructose-1,6-bisphosphatase; Identified by match to protein family HMM PF00316. | 0.924 |
aroA-2 | pfkA | PERMA_1749 | PERMA_1298 | Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.925 |
aroA-2 | pgi | PERMA_1749 | PERMA_1557 | Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family. | 0.832 |
aroA-2 | tal | PERMA_1749 | PERMA_0911 | Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.930 |