node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACO03431.1 | fabD | PERMA_1924 | PERMA_0648 | 2-succinylbenzoate--CoA ligase (OSB-CoA synthetase) (o-succinylbenzoyl-CoA synthetase); Identified by match to protein family HMM PF00501. | Malonyl CoA-acyl carrier protein transacylase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128. | 0.923 |
ACO03431.1 | fabF | PERMA_1924 | PERMA_0509 | 2-succinylbenzoate--CoA ligase (OSB-CoA synthetase) (o-succinylbenzoyl-CoA synthetase); Identified by match to protein family HMM PF00501. | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.944 |
ACO03431.1 | hemL | PERMA_1924 | PERMA_1058 | 2-succinylbenzoate--CoA ligase (OSB-CoA synthetase) (o-succinylbenzoyl-CoA synthetase); Identified by match to protein family HMM PF00501. | Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. | 0.738 |
ACO03620.1 | hemL | PERMA_1059 | PERMA_1058 | Hypothetical protein; Identified by Glimmer3; putative. | Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. | 0.752 |
ACO03620.1 | nrdR | PERMA_1059 | PERMA_1060 | Hypothetical protein; Identified by Glimmer3; putative. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.773 |
ACO04070.1 | hemA | PERMA_0893 | PERMA_1726 | Siroheme synthase; Identified by match to protein family HMM TIGR01470. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.687 |
ACO04070.1 | hemC | PERMA_0893 | PERMA_0444 | Siroheme synthase; Identified by match to protein family HMM TIGR01470. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.853 |
ACO04070.1 | hemD | PERMA_0893 | PERMA_1098 | Siroheme synthase; Identified by match to protein family HMM TIGR01470. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.482 |
ACO04070.1 | hemL | PERMA_0893 | PERMA_1058 | Siroheme synthase; Identified by match to protein family HMM TIGR01470. | Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. | 0.752 |
fabD | ACO03431.1 | PERMA_0648 | PERMA_1924 | Malonyl CoA-acyl carrier protein transacylase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128. | 2-succinylbenzoate--CoA ligase (OSB-CoA synthetase) (o-succinylbenzoyl-CoA synthetase); Identified by match to protein family HMM PF00501. | 0.923 |
fabD | fabF | PERMA_0648 | PERMA_0509 | Malonyl CoA-acyl carrier protein transacylase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128. | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.999 |
fabD | hemB | PERMA_0648 | PERMA_0460 | Malonyl CoA-acyl carrier protein transacylase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128. | Delta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. | 0.457 |
fabD | hemL | PERMA_0648 | PERMA_1058 | Malonyl CoA-acyl carrier protein transacylase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128. | Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. | 0.902 |
fabF | ACO03431.1 | PERMA_0509 | PERMA_1924 | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 2-succinylbenzoate--CoA ligase (OSB-CoA synthetase) (o-succinylbenzoyl-CoA synthetase); Identified by match to protein family HMM PF00501. | 0.944 |
fabF | fabD | PERMA_0509 | PERMA_0648 | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Malonyl CoA-acyl carrier protein transacylase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128. | 0.999 |
fabF | hemL | PERMA_0509 | PERMA_1058 | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. | 0.861 |
hemA | ACO04070.1 | PERMA_1726 | PERMA_0893 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Siroheme synthase; Identified by match to protein family HMM TIGR01470. | 0.687 |
hemA | hemB | PERMA_1726 | PERMA_0460 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Delta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. | 0.858 |
hemA | hemC | PERMA_1726 | PERMA_0444 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.995 |
hemA | hemD | PERMA_1726 | PERMA_1098 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.855 |