node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACO03383.1 | ACO04681.1 | PERMA_1683 | PERMA_0642 | Transcriptional regulator, Crp/Fnr family; Identified by match to protein family HMM PF00027; match to protein family HMM PF00325. | Glutamate synthase [NADPH] large chain (nadph-gogat); Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.459 |
ACO03383.1 | ACO04858.1 | PERMA_1683 | PERMA_1686 | Transcriptional regulator, Crp/Fnr family; Identified by match to protein family HMM PF00027; match to protein family HMM PF00325. | Identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Belongs to the SUA5 family. | 0.773 |
ACO03383.1 | panB | PERMA_1683 | PERMA_1684 | Transcriptional regulator, Crp/Fnr family; Identified by match to protein family HMM PF00027; match to protein family HMM PF00325. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.774 |
ACO03383.1 | proA | PERMA_1683 | PERMA_1682 | Transcriptional regulator, Crp/Fnr family; Identified by match to protein family HMM PF00027; match to protein family HMM PF00325. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.765 |
ACO04681.1 | ACO03383.1 | PERMA_0642 | PERMA_1683 | Glutamate synthase [NADPH] large chain (nadph-gogat); Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Transcriptional regulator, Crp/Fnr family; Identified by match to protein family HMM PF00027; match to protein family HMM PF00325. | 0.459 |
ACO04681.1 | glnA | PERMA_0642 | PERMA_1586 | Glutamate synthase [NADPH] large chain (nadph-gogat); Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. | 0.985 |
ACO04681.1 | gltA | PERMA_0642 | PERMA_0627 | Glutamate synthase [NADPH] large chain (nadph-gogat); Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glutamate synthase (NADPH), homotetrameric; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01316. | 0.999 |
ACO04681.1 | proA | PERMA_0642 | PERMA_1682 | Glutamate synthase [NADPH] large chain (nadph-gogat); Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.886 |
ACO04681.1 | proB | PERMA_0642 | PERMA_1075 | Glutamate synthase [NADPH] large chain (nadph-gogat); Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.456 |
ACO04681.1 | proC | PERMA_0642 | PERMA_0589 | Glutamate synthase [NADPH] large chain (nadph-gogat); Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.512 |
ACO04681.1 | purQ | PERMA_0642 | PERMA_0435 | Glutamate synthase [NADPH] large chain (nadph-gogat); Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.900 |
ACO04858.1 | ACO03383.1 | PERMA_1686 | PERMA_1683 | Identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Belongs to the SUA5 family. | Transcriptional regulator, Crp/Fnr family; Identified by match to protein family HMM PF00027; match to protein family HMM PF00325. | 0.773 |
ACO04858.1 | panB | PERMA_1686 | PERMA_1684 | Identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Belongs to the SUA5 family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.799 |
ACO04858.1 | proA | PERMA_1686 | PERMA_1682 | Identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Belongs to the SUA5 family. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.762 |
atpA_1 | proA | PERMA_0182 | PERMA_1682 | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.842 |
glnA | ACO04681.1 | PERMA_1586 | PERMA_0642 | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. | Glutamate synthase [NADPH] large chain (nadph-gogat); Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.985 |
glnA | gltA | PERMA_1586 | PERMA_0627 | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. | Glutamate synthase (NADPH), homotetrameric; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01316. | 0.948 |
glnA | proA | PERMA_1586 | PERMA_1682 | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.834 |
glnA | purQ | PERMA_1586 | PERMA_0435 | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.910 |
gltA | ACO04681.1 | PERMA_0627 | PERMA_0642 | Glutamate synthase (NADPH), homotetrameric; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01316. | Glutamate synthase [NADPH] large chain (nadph-gogat); Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.999 |