node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACO03656.1 | ACO03751.1 | PERMA_1723 | PERMA_1725 | General secretion pathway protein A. | Conserved hypothetical protein; Identified by match to protein family HMM PF06835. | 0.775 |
ACO03656.1 | aroA | PERMA_1723 | PERMA_1722 | General secretion pathway protein A. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.775 |
ACO03656.1 | hemA | PERMA_1723 | PERMA_1726 | General secretion pathway protein A. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.775 |
ACO03656.1 | lptA | PERMA_1723 | PERMA_1724 | General secretion pathway protein A. | Lipopolysaccharide transport periplasmic protein LptA; Identified by match to protein family HMM PF03968; match to protein family HMM TIGR03002. | 0.775 |
ACO03751.1 | ACO03656.1 | PERMA_1725 | PERMA_1723 | Conserved hypothetical protein; Identified by match to protein family HMM PF06835. | General secretion pathway protein A. | 0.775 |
ACO03751.1 | aroA | PERMA_1725 | PERMA_1722 | Conserved hypothetical protein; Identified by match to protein family HMM PF06835. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.775 |
ACO03751.1 | hemA | PERMA_1725 | PERMA_1726 | Conserved hypothetical protein; Identified by match to protein family HMM PF06835. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.775 |
ACO03751.1 | lptA | PERMA_1725 | PERMA_1724 | Conserved hypothetical protein; Identified by match to protein family HMM PF06835. | Lipopolysaccharide transport periplasmic protein LptA; Identified by match to protein family HMM PF03968; match to protein family HMM TIGR03002. | 0.775 |
ACO04070.1 | hemA | PERMA_0893 | PERMA_1726 | Siroheme synthase; Identified by match to protein family HMM TIGR01470. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.687 |
ACO04070.1 | hemC | PERMA_0893 | PERMA_0444 | Siroheme synthase; Identified by match to protein family HMM TIGR01470. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.853 |
ACO04070.1 | hemD | PERMA_0893 | PERMA_1098 | Siroheme synthase; Identified by match to protein family HMM TIGR01470. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.482 |
ACO04070.1 | hemL | PERMA_0893 | PERMA_1058 | Siroheme synthase; Identified by match to protein family HMM TIGR01470. | Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. | 0.752 |
aroA | ACO03656.1 | PERMA_1722 | PERMA_1723 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | General secretion pathway protein A. | 0.775 |
aroA | ACO03751.1 | PERMA_1722 | PERMA_1725 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Conserved hypothetical protein; Identified by match to protein family HMM PF06835. | 0.775 |
aroA | hemA | PERMA_1722 | PERMA_1726 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.788 |
aroA | lptA | PERMA_1722 | PERMA_1724 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Lipopolysaccharide transport periplasmic protein LptA; Identified by match to protein family HMM PF03968; match to protein family HMM TIGR03002. | 0.782 |
gltX | hemA | PERMA_1911 | PERMA_1726 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.679 |
gltX | hemB | PERMA_1911 | PERMA_0460 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Delta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. | 0.457 |
hemA | ACO03656.1 | PERMA_1726 | PERMA_1723 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | General secretion pathway protein A. | 0.775 |
hemA | ACO03751.1 | PERMA_1726 | PERMA_1725 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Conserved hypothetical protein; Identified by match to protein family HMM PF06835. | 0.775 |