STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOW74394.1Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase C1 family. (448 aa)    
Predicted Functional Partners:
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
       0.698
AOW74392.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.686
AOW75009.1
Peptidase M13; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.662
pepX
X-prolyl-dipeptidyl aminopeptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family.
     
 0.605
AOW74391.1
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
       0.535
nusA
Transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination.
      
 0.527
map
Type I methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
      
 0.497
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
      
 0.487
AOW75125.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.459
rplA
50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
     
 0.448
Your Current Organism:
Pediococcus acidilactici
NCBI taxonomy Id: 1254
Other names: BCRC 80335 [[Pediococcus lolii]], CCUG 32235, CIP 103408, DSM 19927 [[Pediococcus lolii]], DSM 20284, JCM 15055 [[Pediococcus lolii]], LMG 11384, LMG:11384, Lactobacillus sp. Lact11, NCFB 2767, NCIMB 12174, P. acidilactici, Pediococcus lindneri, Pediococcus lolii, Pediococcus lolii Doi et al. 2009, strain B213c, strain Back S213C, strain NGRI 0510Q [[Pediococcus lolii]]
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