STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_391680Squalene and phytoene synthases superfamily protein. (648 aa)    
Predicted Functional Partners:
ACA1_391690
Phytoene dehydrogenase.
 
 0.963
ACA1_035520
SterolC5-desaturase; Belongs to the sterol desaturase family.
  
 
 0.928
ACA1_157860
FAD binding domain containing protein.
   
 
 0.864
ACA1_048170
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
 
 0.843
ACA1_182950
Farnesyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
  
 0.837
ACA1_061420
RhoGEF domain containing protein.
  
 
 0.832
ACA1_219650
Erg28 protein.
   
 
 0.793
ACA1_357490
Erg28 family protein.
   
 
 0.793
ACA1_182840
MATE efflux family subfamily protein.
   
 
 0.783
ACA1_264290
Geranylgeranyl diphosphate synthase 1, putative; Belongs to the FPP/GGPP synthase family.
  
 0.772
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.