STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_369310Protein kinase domain containing protein. (1498 aa)    
Predicted Functional Partners:
ACA1_113580
GTP binding protein.
    
 0.616
ACA1_399920
MAP kinseERK kinase.
   
0.518
ACA1_119470
Mitogen-activated protein kinase kinase.
   
 0.518
ACA1_202460
SRFtype transcription factor (DNA-binding and dimerization domain) domain containing protein.
    
 0.499
ACA1_061110
Uncharacterized protein.
    
 0.499
ACA1_065780
SRFtype transcription factor (DNA-binding and dimerization domain) domain containing protein.
    
 0.499
ACA1_274920
PB1 domain containing protein.
    
 0.496
ACA1_293730
PB1 domain containing protein.
    
 0.496
ACA1_175360
PB1 domain containing protein.
    
 0.496
ACA1_066910
Serine/threonine kinase.
   
 0.466
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.