STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_112510Sphingosine kinase. (579 aa)    
Predicted Functional Partners:
ACA1_292900
Tcomplex protein 1, epsilon subunit.
    
  0.610
ACA1_290270
T-complex protein 1 subunit delta.
    
  0.610
ACA1_369180
PAP2 superfamily domain containing protein.
   
 0.504
ACA1_400540
Sphingosine hydroxylase; Belongs to the sterol desaturase family.
   
 0.499
ACA1_362720
Neutral ceramidase.
    
 0.484
ACA1_063920
Uncharacterized protein.
    
 0.477
ACA1_112890
Sphingosine1-phosphate lyase, putative.
  
 0.464
ACA1_321970
Glutamate decarboxylase; Belongs to the group II decarboxylase family.
  
 0.464
ACA1_068140
Sphinganine1-phosphate aldolase BST1, putative.
  
 0.464
ACA1_059740
T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
    
  0.457
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.