STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_282280Dihydrofolate reductase. (185 aa)    
Predicted Functional Partners:
ACA1_057010
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
 
 
 0.854
ACA1_199730
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
 
 
 0.849
ACA1_369360
Thymidylate synthase.
 
 
 0.848
ACA1_076620
Thymidylate synthase.
 
 
 0.751
ACA1_116430
Thymidine kinase.
  
 
 0.647
ACA1_199830
Glycine cleavage system Pprotein.
    
 0.642
ACA1_173270
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
    
 0.629
ACA1_320960
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
  
 0.628
ACA1_151250
Glycine cleavage Tprotein (Aminomethyl transferase) domain containing protein.
   
 
 0.615
ACA1_270360
Phosphoribosylamine-glycine ligase.
  
  
 0.600
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.