STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_174250RBR-type E3 ubiquitin transferase. (513 aa)    
Predicted Functional Partners:
ACA1_011150
eIF4gamma/eIF5/eIF2-epsilon domain containing protein.
 
      0.795
ACA1_318550
HECTdomain (Ubiquitin-transferase) domain containing protein.
   
 
 0.671
ACA1_119400
eIF4gamma/eIF5/eIF2-epsilon domain containing protein.
 
      0.524
ACA1_077270
RBR-type E3 ubiquitin transferase.
    
0.498
ACA1_368020
RINGbox protein 1, putative.
    
 0.478
ACA1_043310
Rieske domain-containing protein.
    
 0.462
ACA1_248410
Alpha2-macroglobulin domain containing protein.
    
 0.431
ACA1_184040
Ribosomal protein s27a, putative.
    
 0.431
ACA1_149990
Ubiquitin domain containing protein.
    
 0.431
ACA1_068730
Ubiquitinfusion protein.
    
 0.431
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.