STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_109730Replication factor C subunit 1. (977 aa)    
Predicted Functional Partners:
ACA1_040860
DNA replication factor C complex subunit 2, putative.
   
0.996
ACA1_252580
Replication factor C protein.
   
 0.996
ACA1_039460
Replication factor C (Activator 1) 3, putative.
   
 0.993
ACA1_344470
Replication factor c subunit.
   
 0.940
ACA1_376610
DEAD/DEAH box helicase domain containing protein.
   
 0.912
ACA1_175040
Rad17 cell cycle checkpoint protein.
   
 0.887
ACA1_056970
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.886
ACA1_369120
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.886
ACA1_206010
Proliferating cell nuclear antigen, cterminal domain containing protein.
   
 0.886
ACA1_351280
3'5' exonuclease domain containing protein.
   
 0.852
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.