STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCY63766.1Major intrinsic protein; Product inferred by homology to UniProt; Belongs to the MIP/aquaporin (TC 1.A.8) family. (213 aa)    
Predicted Functional Partners:
CCY63750.1
Oxidoreductase aldo/keto reductase family; Product inferred by homology to UniProt.
   
 
 0.829
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.825
CCY62362.1
Ankyrin; Product inferred by homology to UniProt.
  
 0.570
CCY63765.1
Unknown; No significant homology to UniProt.
       0.568
CCY63767.1
Unknown; No significant homology to UniProt.
       0.543
CCY63768.1
Uncharacterized protein; Product inferred by homology to UniProt; Belongs to the multicopper oxidase YfiH/RL5 family.
       0.505
CCY63763.1
Glycoside hydrolase family 3 domain protein; Product inferred by homology to UniProt.
       0.483
CCY63764.1
Unknown; No significant homology to UniProt.
       0.483
grpE
Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.452
CCY63312.1
Regulatory protein UhpC-like protein; Product inferred by homology to UniProt.
 
  
 0.431
Your Current Organism:
Clostridium sp. CAG967
NCBI taxonomy Id: 1262849
Other names: C. sp. CAG:967, Clostridium sp. CAG:967
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