STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDF08781.1L-threonine aldolase; Product inferred by homology to UniProt. (344 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.782
CDF08626.1
Threonine synthase; Product inferred by homology to UniProt.
   
 0.768
CDF07078.1
Threonine dehydratase; Product inferred by homology to UniProt.
   
 
 0.757
CDF08407.1
Aldehyde dehydrogenase; Product inferred by homology to UniProt; Belongs to the aldehyde dehydrogenase family.
     
 0.732
CDF08408.1
Alcohol dehydrogenase iron-dependent; Product inferred by homology to UniProt.
     
 0.705
CDF08245.1
glycine/D-amino acid oxidase deaminating; Product inferred by homology to UniProt.
    
 0.702
folD
Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
  0.678
CDF07720.1
Pyridine nucleotide-disulfide oxidoreductase; Product inferred by homology to UniProt.
    
  0.675
CDF07747.1
Pyridine nucleotide-disulfide oxidoreductase; Product inferred by homology to UniProt.
    
  0.675
prmC
Release factor glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
    
  0.671
Your Current Organism:
Firmicutes bacterium CAG95
NCBI taxonomy Id: 1262988
Other names: F. bacterium CAG:95, Firmicutes bacterium CAG:95
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