STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDA99465.1Citrate synthase; Product inferred by homology to UniProt; Belongs to the citrate synthase family. (448 aa)    
Predicted Functional Partners:
CDA99534.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
 
 0.987
ldh
L-lactate dehydrogenase 1; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.983
CDB01894.1
Isocitrate dehydrogenase [NADP]; Product inferred by homology to UniProt; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.970
atpA
Putative uncharacterized protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes [...]
   
 0.950
accD
acetyl-CoA carboxylase carboxyl transferase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 
 0.934
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.899
CDB00988.1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.893
CDA97936.1
Aldehyde dehydrogenase; Product inferred by homology to UniProt; Belongs to the aldehyde dehydrogenase family.
  
 0.882
CDB00630.1
fe(III) reductase beta subunit; Product inferred by homology to UniProt.
   
 
 0.867
CDB01249.1
3-hydroxybutyryl-CoA dehydratase; Product inferred by homology to UniProt; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.862
Your Current Organism:
Firmicutes bacterium CAG65
NCBI taxonomy Id: 1262994
Other names: F. bacterium CAG:65, Firmicutes bacterium CAG:65
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