node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCQ90629.1 | queE | NITGR_330027 | NITGR_330029 | Cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | Putative Radical-activating enzyme, radical SAM superfamily; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.601 |
CCQ90629.1 | yfhQ | NITGR_330027 | NITGR_330028 | Cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | Putative A/G-specific adenine glycosylase yfhQ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.778 |
CCQ92086.1 | folE | NITGR_950044 | NITGR_910018 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | GTP cyclohydrolase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.957 |
CCQ92086.1 | queC | NITGR_950044 | NITGR_380027 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.937 |
CCQ92086.1 | queE | NITGR_950044 | NITGR_330029 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | Putative Radical-activating enzyme, radical SAM superfamily; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.985 |
CCQ92086.1 | queF | NITGR_950044 | NITGR_1040012 | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.876 |
PTS | folE | NITGR_910017 | NITGR_910018 | 6-pyruvoyl tetrahydrobiopterin synthase. | GTP cyclohydrolase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.980 |
PTS | queC | NITGR_910017 | NITGR_380027 | 6-pyruvoyl tetrahydrobiopterin synthase. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.899 |
PTS | queE | NITGR_910017 | NITGR_330029 | 6-pyruvoyl tetrahydrobiopterin synthase. | Putative Radical-activating enzyme, radical SAM superfamily; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.939 |
PTS | queF | NITGR_910017 | NITGR_1040012 | 6-pyruvoyl tetrahydrobiopterin synthase. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.876 |
folE | CCQ92086.1 | NITGR_910018 | NITGR_950044 | GTP cyclohydrolase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.957 |
folE | PTS | NITGR_910018 | NITGR_910017 | GTP cyclohydrolase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 6-pyruvoyl tetrahydrobiopterin synthase. | 0.980 |
folE | folK | NITGR_910018 | NITGR_610044 | GTP cyclohydrolase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.998 |
folE | queE | NITGR_910018 | NITGR_330029 | GTP cyclohydrolase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative Radical-activating enzyme, radical SAM superfamily; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.561 |
folK | folE | NITGR_610044 | NITGR_910018 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | GTP cyclohydrolase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.998 |
folK | queE | NITGR_610044 | NITGR_330029 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative Radical-activating enzyme, radical SAM superfamily; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.554 |
glmS | purF | NITGR_980018 | NITGR_90026 | Glucosamine--fructose-6-phosphate aminotransferase (isomerizing). | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.635 |
glmS | queC | NITGR_980018 | NITGR_380027 | Glucosamine--fructose-6-phosphate aminotransferase (isomerizing). | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.521 |
glmS | queE | NITGR_980018 | NITGR_330029 | Glucosamine--fructose-6-phosphate aminotransferase (isomerizing). | Putative Radical-activating enzyme, radical SAM superfamily; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.596 |
glmS | queF | NITGR_980018 | NITGR_1040012 | Glucosamine--fructose-6-phosphate aminotransferase (isomerizing). | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.525 |