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SMAR001190-PA protein (Strigamia maritima) - STRING interaction network
"SMAR001190-PA" - Replication protein A subunit in Strigamia maritima
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
SMAR001190-PAReplication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage (1734 aa)    
Predicted Functional Partners:
SMAR004056-PA
annotation not available (1434 aa)
   
  0.998
SMAR008938-PA
annotation not available (1089 aa)
     
  0.995
SMAR013089-PA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (261 aa)
     
  0.994
SMAR007699-PA
annotation not available (907 aa)
     
  0.994
SMAR014454-PA
annotation not available (238 aa)
     
  0.993
SMAR004175-PA
annotation not available (801 aa)
     
  0.992
SMAR007530-PA
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (945 aa)
   
  0.991
SMAR012052-PA
annotation not available (1431 aa)
     
  0.991
SMAR008214-PA
annotation not available (2505 aa)
     
  0.991
SMAR009055-PA
annotation not available (732 aa)
     
  0.991
Your Current Organism:
Strigamia maritima
NCBI taxonomy Id: 126957
Other names: S. maritima, Strigamia maritima
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