STRINGSTRING
HX89_06035 protein (Dermacoccus nishinomiyaensis) - STRING interaction network
"HX89_06035" - Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex in Dermacoccus nishinomiyaensis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HX89_06035Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Derived by automated computational analysis using gene prediction method- Protein Homology (616 aa)    
Predicted Functional Partners:
HX89_08695
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology (466 aa)
  0.992
HX89_10515
Flavoprotein disulfide reductase; Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; Derived by automated computational analysis using gene prediction method- Protein Homology (468 aa)
  0.980
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method- Protein Homology (1278 aa)
 
0.979
HX89_02260
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (465 aa)
  0.969
sucD
Succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit (299 aa)
 
  0.960
sucC
Succinate--CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (394 aa)
   
  0.956
HX89_02115
2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology (346 aa)
 
  0.924
HX89_13010
Acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology (393 aa)
   
    0.919
HX89_02110
Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology (426 aa)
 
 
  0.886
HX89_08960
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (920 aa)
 
 
  0.846
Your Current Organism:
Dermacoccus nishinomiyaensis
NCBI taxonomy Id: 1274
Other names: ATCC 29093, CCM 2140, CCUG 33028, CIP 81.71, D. nishinomiyaensis, DSM 20448, Dermacoccus nishinomiyaensis, Dermacoccus nishinomiyensis, Dermatococcus nishinomiyaensis, Dermatococcus nishinomiyensis, IEGM 393, IFO 15356, JCM 11613, LMG 14222, Micrococcus nishinomiyaensis, Micrococcus nishinomyaensis, NBRC 15356, NCTC 11039
Server load: low (11%) [HD]