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sbcD protein (Dermacoccus nishinomiyaensis) - STRING interaction network
"sbcD" - Nuclease SbcCD subunit D in Dermacoccus nishinomiyaensis
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcDNuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3’->5’ double strand exonuclease that can open hairpins. It also has a 5’ single-strand endonuclease activity (397 aa)    
Predicted Functional Partners:
HX89_07085
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (1196 aa)
 
 
  0.998
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA super [...] (940 aa)
   
 
  0.848
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (364 aa)
   
 
  0.783
HX89_07080
Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method- Protein Homology (417 aa)
              0.765
HX89_13400
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (1119 aa)
   
 
  0.702
HX89_06140
Endonuclease; Derived by automated computational analysis using gene prediction method- Protein Homology (608 aa)
   
   
  0.682
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (889 aa)
   
 
  0.642
HX89_04510
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the helicase family. UvrD subfamily (1176 aa)
   
 
  0.605
HX89_04505
UvrD/REP helicase; Derived by automated computational analysis using gene prediction method- Protein Homology (1117 aa)
   
 
  0.605
HX89_07095
Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method- Protein Homology (194 aa)
   
        0.586
Your Current Organism:
Dermacoccus nishinomiyaensis
NCBI taxonomy Id: 1274
Other names: ATCC 29093, CCM 2140, CCUG 33028, CIP 81.71, D. nishinomiyaensis, DSM 20448, Dermacoccus nishinomiyaensis, Dermacoccus nishinomiyensis, Dermatococcus nishinomiyaensis, Dermatococcus nishinomiyensis, IEGM 393, IFO 15356, JCM 11613, LMG 14222, Micrococcus nishinomiyaensis, Micrococcus nishinomyaensis, NBRC 15356, NCTC 11039
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