STRINGSTRING
fpg protein (Dermacoccus nishinomiyaensis) - STRING interaction network
"fpg" - Formamidopyrimidine-DNA glycosylase in Dermacoccus nishinomiyaensis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fpgFormamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3’- and 5’-phosphates (348 aa)    
Predicted Functional Partners:
rnc
Ribonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism (272 aa)
   
        0.890
HX89_09795
Metal-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology (193 aa)
   
   
  0.868
HX89_01325
DNA lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the FPG family (287 aa)
   
   
0.864
rpmF
50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the bacterial ribosomal protein bL32 family (64 aa)
              0.860
HX89_07865
Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family (195 aa)
 
   
  0.841
HX89_00955
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (304 aa)
   
   
  0.828
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (889 aa)
 
   
  0.809
HX89_09805
Methyltransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (223 aa)
 
      0.739
HX89_09810
ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method- Protein Homology (729 aa)
   
   
  0.694
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4’- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate; Belongs to the bacterial CoaD family (161 aa)
         
  0.682
Your Current Organism:
Dermacoccus nishinomiyaensis
NCBI taxonomy Id: 1274
Other names: ATCC 29093, CCM 2140, CCUG 33028, CIP 81.71, D. nishinomiyaensis, DSM 20448, Dermacoccus nishinomiyaensis, Dermacoccus nishinomiyensis, Dermatococcus nishinomiyaensis, Dermatococcus nishinomiyensis, IEGM 393, IFO 15356, JCM 11613, LMG 14222, Micrococcus nishinomiyaensis, Micrococcus nishinomyaensis, NBRC 15356, NCTC 11039
Server load: low (3%) [HD]