STRINGSTRING
HX89_10740 protein (Dermacoccus nishinomiyaensis) - STRING interaction network
"HX89_10740" - Isocitrate dehydrogenase [NADP] in Dermacoccus nishinomiyaensis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HX89_10740Isocitrate dehydrogenase [NADP]; Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family (406 aa)    
Predicted Functional Partners:
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method- Protein Homology (1278 aa)
     
 
  0.992
acnA
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (934 aa)
   
  0.965
HX89_08145
Glutamate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (1511 aa)
       
  0.944
HX89_04100
Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family (449 aa)
     
  0.877
HX89_01895
Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines- the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method- Protein Homology (473 aa)
   
 
  0.824
HX89_12930
Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology (461 aa)
   
 
  0.820
HX89_12925
Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the aldehyde dehydrogenase family (484 aa)
   
 
  0.820
gabD2
NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; Derived by automated computational analysis using gene prediction method- Protein Homology (526 aa)
   
 
  0.820
HX89_01995
Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology (456 aa)
   
 
  0.820
HX89_07080
Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method- Protein Homology (417 aa)
   
 
  0.820
Your Current Organism:
Dermacoccus nishinomiyaensis
NCBI taxonomy Id: 1274
Other names: ATCC 29093, CCM 2140, CCUG 33028, CIP 81.71, D. nishinomiyaensis, DSM 20448, Dermacoccus nishinomiyaensis, Dermacoccus nishinomiyensis, Dermatococcus nishinomiyaensis, Dermatococcus nishinomiyensis, IEGM 393, IFO 15356, JCM 11613, LMG 14222, Micrococcus nishinomiyaensis, Micrococcus nishinomyaensis, NBRC 15356, NCTC 11039
Server load: low (7%) [HD]