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tilS protein (Dermacoccus nishinomiyaensis) - STRING interaction network
"tilS" - tRNA(Ile)-lysidine synthase in Dermacoccus nishinomiyaensis
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine; Belongs to the tRNA(Ile)-lysidine synthase family (353 aa)    
Predicted Functional Partners:
HX89_12600
Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family (183 aa)
 
   
  0.973
HX89_12610
Coenzyme F420 biosynthesis protein; Derived by automated computational analysis using gene prediction method- Protein Homology (351 aa)
   
        0.892
nnrD
ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; In the C-terminal section; belongs to the NnrD/CARKD family (522 aa)
   
   
  0.805
lysS
Lysine--tRNA ligase; Catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family (1108 aa)
   
   
  0.737
HX89_12580
7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin (323 aa)
   
        0.728
tadA
tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family (159 aa)
 
   
  0.672
HX89_10675
Acetylneuraminic acid synthetase; Derived by automated computational analysis using gene prediction method- Protein Homology (760 aa)
   
 
  0.643
ftsH
ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family (682 aa)
   
   
  0.626
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box)- 5’-TTATC[CA]A[CA]A-3’. DnaA binds to ATP and to acidic phospholipids (501 aa)
 
     
  0.622
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family (192 aa)
 
   
  0.616
Your Current Organism:
Dermacoccus nishinomiyaensis
NCBI taxonomy Id: 1274
Other names: ATCC 29093, CCM 2140, CCUG 33028, CIP 81.71, D. nishinomiyaensis, DSM 20448, Dermacoccus nishinomiyaensis, Dermacoccus nishinomiyensis, Dermatococcus nishinomiyaensis, Dermatococcus nishinomiyensis, IEGM 393, IFO 15356, JCM 11613, LMG 14222, Micrococcus nishinomiyaensis, Micrococcus nishinomyaensis, NBRC 15356, NCTC 11039
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