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nth protein (Dermacoccus nishinomiyaensis) - STRING interaction network
"nth" - Endonuclease III in Dermacoccus nishinomiyaensis
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (277 aa)    
Predicted Functional Partners:
HX89_12800
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method- Protein Homology (226 aa)
   
 
  0.904
HX89_10760
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method- Protein Homology (269 aa)
 
 
 
  0.831
HX89_12810
Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method- Protein Homology (225 aa)
 
   
  0.733
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (889 aa)
   
 
  0.732
HX89_06140
Endonuclease; Derived by automated computational analysis using gene prediction method- Protein Homology (608 aa)
   
   
  0.697
fpg
Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3’- and 5’-phosphates (348 aa)
   
   
  0.612
HX89_00955
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (304 aa)
   
   
  0.609
HX89_08580
Putative 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the DNA glycosylase MPG family (212 aa)
     
   
  0.541
HX89_12120
DNA glycosylase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the FPG family (289 aa)
   
   
  0.538
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (224 aa)
 
 
  0.535
Your Current Organism:
Dermacoccus nishinomiyaensis
NCBI taxonomy Id: 1274
Other names: ATCC 29093, CCM 2140, CCUG 33028, CIP 81.71, D. nishinomiyaensis, DSM 20448, Dermacoccus nishinomiyaensis, Dermacoccus nishinomiyensis, Dermatococcus nishinomiyaensis, Dermatococcus nishinomiyensis, IEGM 393, IFO 15356, JCM 11613, LMG 14222, Micrococcus nishinomiyaensis, Micrococcus nishinomyaensis, NBRC 15356, NCTC 11039
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