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fhs protein (Dermacoccus nishinomiyaensis) - STRING interaction network
"fhs" - Formate--tetrahydrofolate ligase in Dermacoccus nishinomiyaensis
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
fhsFormate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the formate--tetrahydrofolate ligase family (557 aa)    
Predicted Functional Partners:
folD
Bifunctional protein FolD; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (285 aa)
 
 
  0.994
HX89_07440
Methionine synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (1262 aa)
       
  0.979
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (424 aa)
   
  0.967
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (231 aa)
   
 
  0.945
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine (367 aa)
   
 
  0.933
HX89_05605
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (165 aa)
   
 
  0.924
purH
Bifunctional purine biosynthesis protein PurH; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology (536 aa)
   
 
  0.878
HX89_11615
2,4-dienoyl-CoA reductase; Derived by automated computational analysis using gene prediction method- Protein Homology (714 aa)
   
   
  0.666
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family (955 aa)
   
   
  0.615
HX89_06525
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology (709 aa)
     
   
  0.615
Your Current Organism:
Dermacoccus nishinomiyaensis
NCBI taxonomy Id: 1274
Other names: ATCC 29093, CCM 2140, CCUG 33028, CIP 81.71, D. nishinomiyaensis, DSM 20448, Dermacoccus nishinomiyaensis, Dermacoccus nishinomiyensis, Dermatococcus nishinomiyaensis, Dermatococcus nishinomiyensis, IEGM 393, IFO 15356, JCM 11613, LMG 14222, Micrococcus nishinomiyaensis, Micrococcus nishinomyaensis, NBRC 15356, NCTC 11039
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