node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HPO_11898 | engB | HPO_11898 | HPO_01697 | Iojap family protein; COG0799 Uncharacterized homolog of plant Iojap protein. | GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.941 |
HPO_11898 | mnmE | HPO_11898 | HPO_09003 | Iojap family protein; COG0799 Uncharacterized homolog of plant Iojap protein. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.927 |
HPO_11898 | rplC | HPO_11898 | HPO_00015 | Iojap family protein; COG0799 Uncharacterized homolog of plant Iojap protein. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.956 |
HPO_11898 | rplM | HPO_11898 | HPO_15713 | Iojap family protein; COG0799 Uncharacterized homolog of plant Iojap protein. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.956 |
HPO_11898 | rplN | HPO_11898 | HPO_00065 | Iojap family protein; COG0799 Uncharacterized homolog of plant Iojap protein. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.971 |
HPO_11898 | rplO | HPO_11898 | HPO_00110 | Iojap family protein; COG0799 Uncharacterized homolog of plant Iojap protein. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.956 |
HPO_11898 | rplQ | HPO_11898 | HPO_00140 | Iojap family protein; COG0799 Uncharacterized homolog of plant Iojap protein. | COG0203 Ribosomal protein L17. | 0.956 |
HPO_11898 | rplU | HPO_11898 | HPO_07817 | Iojap family protein; COG0799 Uncharacterized homolog of plant Iojap protein. | 50S ribosomal protein L21/unknown domain fusion protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.971 |
HPO_11898 | rplX | HPO_11898 | HPO_00070 | Iojap family protein; COG0799 Uncharacterized homolog of plant Iojap protein. | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.968 |
engB | HPO_11898 | HPO_01697 | HPO_11898 | GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Iojap family protein; COG0799 Uncharacterized homolog of plant Iojap protein. | 0.941 |
engB | mnmE | HPO_01697 | HPO_09003 | GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.950 |
engB | rplC | HPO_01697 | HPO_00015 | GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.933 |
engB | rplM | HPO_01697 | HPO_15713 | GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.928 |
engB | rplN | HPO_01697 | HPO_00065 | GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.933 |
engB | rplO | HPO_01697 | HPO_00110 | GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.956 |
engB | rplQ | HPO_01697 | HPO_00140 | GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | COG0203 Ribosomal protein L17. | 0.935 |
engB | rplU | HPO_01697 | HPO_07817 | GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal protein L21/unknown domain fusion protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.934 |
engB | rplX | HPO_01697 | HPO_00070 | GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.932 |
engB | yidC | HPO_01697 | HPO_01692 | GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Inner membrane protein, 60 kDa; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.940 |
mnmE | HPO_11898 | HPO_09003 | HPO_11898 | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Iojap family protein; COG0799 Uncharacterized homolog of plant Iojap protein. | 0.927 |