node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
S40285_00171 | S40285_01432 | A0A084QU14 | A0A084QLB9 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | 0.998 |
S40285_00171 | S40285_02771 | A0A084QU14 | A0A084QAJ0 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | BRCT domain-containing protein. | 0.977 |
S40285_00171 | S40285_04337 | A0A084QU14 | A0A084QNP4 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | BRCT domain-containing protein. | 0.951 |
S40285_00171 | S40285_06255 | A0A084QU14 | A0A084QSP8 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Protein kinase domain-containing protein. | 0.457 |
S40285_00171 | S40285_07622 | A0A084QU14 | A0A084QAW9 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Uncharacterized protein. | 0.851 |
S40285_00790 | S40285_02771 | A0A084QJP4 | A0A084QAJ0 | Protein kinase domain-containing protein. | BRCT domain-containing protein. | 0.807 |
S40285_00790 | S40285_04337 | A0A084QJP4 | A0A084QNP4 | Protein kinase domain-containing protein. | BRCT domain-containing protein. | 0.590 |
S40285_00790 | S40285_05056 | A0A084QJP4 | A0A084Q9N6 | Protein kinase domain-containing protein. | Protein kinase domain-containing protein. | 0.708 |
S40285_00790 | S40285_06255 | A0A084QJP4 | A0A084QSP8 | Protein kinase domain-containing protein. | Protein kinase domain-containing protein. | 0.998 |
S40285_00790 | S40285_06396 | A0A084QJP4 | A0A084QGG6 | Protein kinase domain-containing protein. | Rhodanese domain-containing protein. | 0.833 |
S40285_00790 | S40285_07622 | A0A084QJP4 | A0A084QAW9 | Protein kinase domain-containing protein. | Uncharacterized protein. | 0.837 |
S40285_00790 | S40285_07914 | A0A084QJP4 | A0A084QDF6 | Protein kinase domain-containing protein. | Rhodanese domain-containing protein. | 0.833 |
S40285_01432 | S40285_00171 | A0A084QLB9 | A0A084QU14 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.998 |
S40285_01432 | S40285_02771 | A0A084QLB9 | A0A084QAJ0 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | BRCT domain-containing protein. | 0.988 |
S40285_01432 | S40285_04337 | A0A084QLB9 | A0A084QNP4 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | BRCT domain-containing protein. | 0.949 |
S40285_01432 | S40285_05056 | A0A084QLB9 | A0A084Q9N6 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | Protein kinase domain-containing protein. | 0.987 |
S40285_01432 | S40285_05794 | A0A084QLB9 | A0A084QAC8 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | RFX-type winged-helix domain-containing protein. | 0.937 |
S40285_01432 | S40285_06255 | A0A084QLB9 | A0A084QSP8 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | Protein kinase domain-containing protein. | 0.706 |
S40285_01432 | S40285_06396 | A0A084QLB9 | A0A084QGG6 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | Rhodanese domain-containing protein. | 0.706 |
S40285_01432 | S40285_07622 | A0A084QLB9 | A0A084QAW9 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | Uncharacterized protein. | 0.926 |