node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHM57089.1 | ddl | EAL2_c17970 | EAL2_c17990 | Hypothetical protein. | D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.656 |
AHM57089.1 | ispE | EAL2_c17970 | EAL2_c18010 | Hypothetical protein. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.484 |
AHM57089.1 | murI | EAL2_c17970 | EAL2_c17980 | Hypothetical protein. | Glutamate racemase MurI; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.661 |
ddl | AHM57089.1 | EAL2_c17990 | EAL2_c17970 | D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Hypothetical protein. | 0.656 |
ddl | ispE | EAL2_c17990 | EAL2_c18010 | D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.589 |
ddl | murB | EAL2_c17990 | EAL2_c04480 | D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylenolpyruvoylglucosamine reductase MurB; Cell wall formation. | 0.997 |
ddl | murC | EAL2_c17990 | EAL2_c02080 | D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family. | 0.978 |
ddl | murD | EAL2_c17990 | EAL2_c10460 | D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.846 |
ddl | murE | EAL2_c17990 | EAL2_c10430 | D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase MurE; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.669 |
ddl | murF | EAL2_c17990 | EAL2_c10440 | D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.994 |
ddl | murG | EAL2_c17990 | EAL2_c10480 | D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.844 |
ddl | murI | EAL2_c17990 | EAL2_c17980 | D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Glutamate racemase MurI; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.871 |
ispE | AHM57089.1 | EAL2_c18010 | EAL2_c17970 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Hypothetical protein. | 0.484 |
ispE | ddl | EAL2_c18010 | EAL2_c17990 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.589 |
ispE | murI | EAL2_c18010 | EAL2_c17980 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Glutamate racemase MurI; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.536 |
murB | ddl | EAL2_c04480 | EAL2_c17990 | UDP-N-acetylenolpyruvoylglucosamine reductase MurB; Cell wall formation. | D-alanine--D-alanine ligase Ddl; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.997 |
murB | murC | EAL2_c04480 | EAL2_c02080 | UDP-N-acetylenolpyruvoylglucosamine reductase MurB; Cell wall formation. | UDP-N-acetylmuramate--L-alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family. | 0.998 |
murB | murD | EAL2_c04480 | EAL2_c10460 | UDP-N-acetylenolpyruvoylglucosamine reductase MurB; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.850 |
murB | murE | EAL2_c04480 | EAL2_c10430 | UDP-N-acetylenolpyruvoylglucosamine reductase MurB; Cell wall formation. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase MurE; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.820 |
murB | murF | EAL2_c04480 | EAL2_c10440 | UDP-N-acetylenolpyruvoylglucosamine reductase MurB; Cell wall formation. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.835 |