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hisI protein (Staphylococcus xylosus) - STRING interaction network
"hisI" - Histidine biosynthesis bifunctional protein HisIE in Staphylococcus xylosus
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisIHistidine biosynthesis bifunctional protein HisIE; Phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family (210 aa)    
Predicted Functional Partners:
hisA
annotation not available (234 aa)
 
  0.999
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (252 aa)
   
  0.999
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity; Belongs to the ATP phosphoribosyltransferase family. Short subfamily (205 aa)
 
 
  0.999
hisB
annotation not available (192 aa)
   
  0.999
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (419 aa)
   
  0.999
AID41894.1
annotation not available (334 aa)
   
  0.999
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (198 aa)
 
   
  0.999
hisZ
annotation not available (271 aa)
 
   
  0.996
hisC
annotation not available (351 aa)
   
  0.986
argH
annotation not available (458 aa)
   
   
  0.904
Your Current Organism:
Staphylococcus xylosus
NCBI taxonomy Id: 1288
Other names: ATCC 29971, CCUG 7324, CIP 81.66, DSM 20266, HAMBI 2057, JCM 2418, NCTC 11043, NRRL B-14776, S. xylosus, Staphylococcus xylosus
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