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ezrA protein (Staphylococcus xylosus) - STRING interaction network
"ezrA" - Septation ring formation regulator EzrA in Staphylococcus xylosus
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ezrASeptation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (563 aa)    
Predicted Functional Partners:
AID42769.1
Cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (119 aa)
   
 
 
  0.924
AID42671.1
Transpeptidase, Penicillin binding protein transpeptidase domain (683 aa)
   
     
  0.866
ftsL
Cell division protein FtsL; Essential cell division protein (130 aa)
   
     
  0.820
AID42522.1
annotation not available (315 aa)
 
          0.800
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring; Belongs to the FtsA/MreB family (475 aa)
   
 
 
  0.791
AID43689.1
annotation not available (132 aa)
   
     
  0.786
AID43062.1
annotation not available (716 aa)
   
     
  0.783
AID43089.1
Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (88 aa)
 
 
 
  0.757
AID42432.1
annotation not available (407 aa)
   
          0.746
AID42612.1
UPF0473 protein AST15_00600; FIG01108372; Belongs to the UPF0473 family (110 aa)
   
          0.735
Your Current Organism:
Staphylococcus xylosus
NCBI taxonomy Id: 1288
Other names: ATCC 29971, CCUG 7324, CIP 81.66, DSM 20266, HAMBI 2057, JCM 2418, NCTC 11043, NRRL B-14776, S. xylosus, Staphylococcus xylosus
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