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mprF protein (Staphylococcus xylosus) - STRING interaction network
"mprF" - Phosphatidylglycerol lysyltransferase in Staphylococcus xylosus
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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mprFPhosphatidylglycerol lysyltransferase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host’s immune system (defensins, cathelicidins) and by the competing microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with pos [...] (841 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase subunit beta’; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1207 aa)
     
   
  0.793
AID42952.1
annotation not available (192 aa)
   
   
  0.757
AID43230.1
Homology with SAS0844 (592 aa)
 
   
  0.747
AID43273.1
annotation not available (404 aa)
 
   
  0.679
AID43412.1
Lipoteichoic acid synthase; Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate (646 aa)
         
  0.676
AID43173.1
Autolysin; N-acetylmuramoyl-L-alanine amidase; endo-beta-N-acetylglucosaminidase (1533 aa)
   
     
  0.647
AID42260.1
Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (494 aa)
   
   
  0.643
AID41647.1
Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (494 aa)
   
   
  0.643
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1183 aa)
     
   
  0.639
lysS
annotation not available (495 aa)
       
  0.633
Your Current Organism:
Staphylococcus xylosus
NCBI taxonomy Id: 1288
Other names: ATCC 29971, CCUG 7324, CIP 81.66, DSM 20266, HAMBI 2057, JCM 2418, NCTC 11043, NRRL B-14776, S. xylosus, Staphylococcus xylosus
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