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menD protein (Staphylococcus xylosus) - STRING interaction network
"menD" - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase in Staphylococcus xylosus
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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menD2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC); Belongs to the TPP enzyme family. MenD subfamily (560 aa)    
Predicted Functional Partners:
AID43179.1
annotation not available (250 aa)
 
  0.999
AID43181.1
annotation not available (450 aa)
 
  0.998
menB
1,4-dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) (272 aa)
 
   
  0.983
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily (312 aa)
 
     
  0.962
AID42446.1
annotation not available (334 aa)
 
     
  0.764
menE
2-succinylbenzoate--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl- CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily (459 aa)
 
     
  0.726
AID43262.1
Thioesterase; FIG01108366 (125 aa)
 
     
  0.599
AID42566.1
annotation not available (309 aa)
           
  0.552
AID43443.1
annotation not available (547 aa)
           
  0.493
menG
Demethylmenaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) (233 aa)
         
  0.484
Your Current Organism:
Staphylococcus xylosus
NCBI taxonomy Id: 1288
Other names: ATCC 29971, CCUG 7324, CIP 81.66, DSM 20266, HAMBI 2057, JCM 2418, NCTC 11043, NRRL B-14776, S. xylosus, Staphylococcus xylosus
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